Active immunization using a single dose immunotherapeutic abates established EAE via IL-10 and regulatory T cells

Stimulation of Ag-specific inducible Treg can enhance resolution of autoimmune disease. Conventional methods to induce Treg often require induction of autoimmune disease or subjection to infection. Reovirus adhesin, protein σ1 (pσ1), can successfully facilitate tolerance when fused to a tolerogen. W...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rynda-Apple, Agnieszka, Huarte, Eduardo, Maddaloni, Massimo, Callis, Gayle, Skyberg, Jerod A., Pascual, David W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145764/
https://ncbi.nlm.nih.gov/pubmed/21268002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041104
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