Autoimmune regulator (AIRE)-deficient CD8(+)CD28(low) regulatory T lymphocytes fail to control experimental colitis

Mutations in the gene encoding the transcription factor autoimmune regulator (AIRE) are responsible for autoimmune polyendocrinopathy candidiasis ectodermal dystrophy syndrome. AIRE directs expression of tissue-restricted antigens in the thymic medulla and in lymph node stromal cells and thereby sub...

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Main Authors: Pomié, Céline, Vicente, Rita, Vuddamalay, Yirajen, Lundgren, Brita Ardesjö, van der Hoek, Mark, Enault, Geneviève, Kagan, Jérémy, Fazilleau, Nicolas, Scott, Hamish S., Romagnoli, Paola, van Meerwijk, Joost P. M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145727/
https://ncbi.nlm.nih.gov/pubmed/21746930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107136108
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