Autoimmune regulator (AIRE)-deficient CD8(+)CD28(low) regulatory T lymphocytes fail to control experimental colitis

Mutations in the gene encoding the transcription factor autoimmune regulator (AIRE) are responsible for autoimmune polyendocrinopathy candidiasis ectodermal dystrophy syndrome. AIRE directs expression of tissue-restricted antigens in the thymic medulla and in lymph node stromal cells and thereby sub...

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Bibliografiska uppgifter
Huvudupphovsmän: Pomié, Céline, Vicente, Rita, Vuddamalay, Yirajen, Lundgren, Brita Ardesjö, van der Hoek, Mark, Enault, Geneviève, Kagan, Jérémy, Fazilleau, Nicolas, Scott, Hamish S., Romagnoli, Paola, van Meerwijk, Joost P. M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145727/
https://ncbi.nlm.nih.gov/pubmed/21746930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107136108
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