Autoimmune regulator (AIRE)-deficient CD8(+)CD28(low) regulatory T lymphocytes fail to control experimental colitis

Mutations in the gene encoding the transcription factor autoimmune regulator (AIRE) are responsible for autoimmune polyendocrinopathy candidiasis ectodermal dystrophy syndrome. AIRE directs expression of tissue-restricted antigens in the thymic medulla and in lymph node stromal cells and thereby sub...

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Main Authors: Pomié, Céline, Vicente, Rita, Vuddamalay, Yirajen, Lundgren, Brita Ardesjö, van der Hoek, Mark, Enault, Geneviève, Kagan, Jérémy, Fazilleau, Nicolas, Scott, Hamish S., Romagnoli, Paola, van Meerwijk, Joost P. M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2011
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145727/
https://ncbi.nlm.nih.gov/pubmed/21746930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107136108
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