Lataa...

The Synthesis and Evaluation of N(1)-(4-(2-[(18)F]-fluoroethyl)phenyl)-N(8)-hydroxyoctanediamide ([(18)F]-FESAHA), A PET Radiotracer Designed for the Delineation of Histone Deacetylase Expression in Cancer

INTRODUCTION: Given the significant utility of suberoylanilide hydroxamic acid (SAHA) in chemotherapeutic protocols, a PET tracer that mimics the histone deacetylase (HDAC) inhibition of SAHA could be a valuable tool in the diagnosis, treatment planning, and treatment monitoring of cancer. Here, we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zeglis, Brian M., Pillarsetty, NagaVara Kishore, Divilov, Vadim, Blasberg, Ronald A., Lewis, Jason S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145497/
https://ncbi.nlm.nih.gov/pubmed/21718944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.12.008
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!