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TMSOTf assisted synthesis of 2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine ([(18)F]FAC)
[(18)F]FAC (2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine, 1) is a versatile probe for imaging deoxycytidine kinase (dCK) expression levels in vivo. dCK is responsible for phosphorylation of deoxycytidine (dC, 2) and other nucleoside analogs, plays a key role in immune activation and has de...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929562/ https://ncbi.nlm.nih.gov/pubmed/29715301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196784 |
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