TMSOTf assisted synthesis of 2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine ([(18)F]FAC)

[(18)F]FAC (2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine, 1) is a versatile probe for imaging deoxycytidine kinase (dCK) expression levels in vivo. dCK is responsible for phosphorylation of deoxycytidine (dC, 2) and other nucleoside analogs, plays a key role in immune activation and has de...

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Udgivet i:PLoS One
Main Authors: Gangangari, Kishore K., Humm, John L., Larson, Steven M., Pillarsetty, Naga Vara Kishore
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929562/
https://ncbi.nlm.nih.gov/pubmed/29715301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196784
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