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Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)

The β-subunits of the voltage-gated potassium channel (Kvβ) belong to the aldo-keto reductase superfamily. The Kvβ-subunits dock with the pore-forming Kv α-subunits and impart or accelerate the rate of inactivation in Kv channels. Inactivation of Kv currents by Kvβ is differentially regulated by oxi...

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Autors principals: Xie, Zhengzhi, Barski, Oleg A., Cai, Jian, Bhatnagar, Aruni, Tipparaju, Srinivas M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145408/
https://ncbi.nlm.nih.gov/pubmed/21296056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2011.01.032
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