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Improving Proteome Coverage on a LTQ-Orbitrap Using Design of Experiments

Design of experiments (DOE) was used to determine improved settings for a LTQ-Orbitrap XL to maximize proteome coverage of Saccharomyces cerevisiae. A total of nine instrument parameters were evaluated with the best values affording an increase of approximately 60% in proteome coverage. Utilizing JM...

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Detalhes bibliográficos
Main Authors: Andrews, Genna L., Dean, Ralph A., Hawkridge, Adam M., Muddiman, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145359/
https://ncbi.nlm.nih.gov/pubmed/21472614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0075-2
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