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The Inhibition of Glycogen Synthase Kinase 3 beta Ameliorates Liver Ischemia Reperfusion Injury via an IL-10-mediated Immune Regulatory Mechanism

The ubiquitous serine/threnine kinase glycogen synthase kinase 3β (Gsk3β) differentially regulates macrophage TLR-triggered pro- and anti-inflammatory cytokine programs. This study was designed to determine in vivo role and therapeutic potential of Gsk3β modulation in tissue inflammation and injury...

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Detalhes bibliográficos
Main Authors: Ren, Feng, Duan, Zhongping, Cheng, Qiao, Shen, Xiuda, Gao, Feng, Bai, Li, Liu, Jun, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W., Zhai, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145016/
https://ncbi.nlm.nih.gov/pubmed/21567437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24419
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