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A Transition Zone Complex Regulates Mammalian Ciliogenesis and Ciliary Membrane Composition
Mutations in genes encoding ciliary components cause ciliopathies, but how many of these mutations disrupt ciliary function is unclear. We investigated Tectonic1 (Tctn1), a regulator of mouse Hedgehog signaling, and found that it is essential for ciliogenesis in some, but not all, tissues. Cell type...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145011/ https://ncbi.nlm.nih.gov/pubmed/21725307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.891 |
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