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Targeted Ablation of Oligodendrocytes Triggers Axonal Damage

Glial dysfunction has been implicated in a number of neurodegenerative diseases. In this study we investigated the consequences of glial and oligodendrocyte ablation on neuronal integrity and survival in Drosophila and adult mice, respectively. Targeted genetic ablation of glia was achieved in the a...

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Detalhes bibliográficos
Main Authors: Ghosh, Aniket, Manrique-Hoyos, Natalia, Voigt, Aaron, Schulz, Jörg B., Kreutzfeldt, Mario, Merkler, Doron, Simons, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144945/
https://ncbi.nlm.nih.gov/pubmed/21818378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022735
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