Targeted Ablation of Oligodendrocytes Induces Axonal Pathology Independent of Overt Demyelination

The critical role of oligodendrocytes in producing and maintaining myelin that supports rapid axonal conduction in CNS neurons is well established. More recently, additional roles for oligodendrocytes have been posited, including provision of trophic factors and metabolic support for neurons. To inv...

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Vydáno v:J Neurosci
Hlavní autoři: Oluich, Laura-Jane, Stratton, Jo Anne S., Lulu Xing, Yao, Ng, Sze Woei, Cate, Holly S., Sah, Pankaj, Windels, François, Kilpatrick, Trevor J., Merson, Tobias D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703635/
https://ncbi.nlm.nih.gov/pubmed/22699912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1053-12.2012
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