Targeted Ablation of Oligodendrocytes Induces Axonal Pathology Independent of Overt Demyelination

The critical role of oligodendrocytes in producing and maintaining myelin that supports rapid axonal conduction in CNS neurons is well established. More recently, additional roles for oligodendrocytes have been posited, including provision of trophic factors and metabolic support for neurons. To inv...

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Pubblicato in:J Neurosci
Autori principali: Oluich, Laura-Jane, Stratton, Jo Anne S., Lulu Xing, Yao, Ng, Sze Woei, Cate, Holly S., Sah, Pankaj, Windels, François, Kilpatrick, Trevor J., Merson, Tobias D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703635/
https://ncbi.nlm.nih.gov/pubmed/22699912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1053-12.2012
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