Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models

Clinical data suggest that progestins have chemopreventive properties in the development of colorectal cancer. We set out to examine a potential protective effect of progestins and progesterone signaling on colon cancer development. In normal and neoplastic intestinal tissue, we found that the proge...

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Detalhes bibliográficos
Main Authors: Heijmans, Jarom, Muncan, Vanesa, Jacobs, Rutger J., de Jonge-Muller, Eveline S. M., Graven, Laura, Biemond, Izak, Ederveen, Antwan G., Groothuis, Patrick G., Mosselman, Sietse, Hardwick, James C., Hommes, Daniel W., van den Brink, Gijs R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144908/
https://ncbi.nlm.nih.gov/pubmed/21818351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022620
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