Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis

AIM: To investigate if azathioprine could reduce adenoma formation in Apc(Min/+), a mouse model of sporadic intestinal tumorigenesis. METHODS: Azathioprine was administered via drinking water (estimated 6-20 mg/kg body weight per day) to Apc(Min/+) and wildtype mice. Control animals received vehicle...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Wielenga, Mattheus CB, van Lidth de Jeude, Jooske F, Rosekrans, Sanne L, Levin, Alon D, Schukking, Monique, D’Haens, Geert RAM, Heijmans, Jarom, Jansen, Marnix, Muncan, Vanesa, van den Brink, Gijs R
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248212/
https://ncbi.nlm.nih.gov/pubmed/25469037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i44.16683
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