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Progressive Reduction of its Expression in Rods Reveals Two Pools of Arrestin-1 in the Outer Segment with Different Roles in Photoresponse Recovery

Light-induced rhodopsin signaling is turned off with sub-second kinetics by rhodopsin phosphorylation followed by arrestin-1 binding. To test the availability of the arrestin-1 pool in dark-adapted outer segment (OS) for rhodopsin shutoff, we measured photoresponse recovery rates of mice with arrest...

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Main Authors: Cleghorn, Whitney M., Tsakem, Elviche L., Song, Xiufeng, Vishnivetskiy, Sergey A., Seo, Jungwon, Chen, Jeannie, Gurevich, Eugenia V., Gurevich, Vsevolod V.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144249/
https://ncbi.nlm.nih.gov/pubmed/21818392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022797
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