MicroRNA-Restricted Transgene Expression in the Retina

BACKGROUND: Gene transfer using adeno-associated viral (AAV) vectors has been successfully applied in the retina for the treatment of inherited retinal dystrophies. Recently, microRNAs have been exploited to fine-tune transgene expression improving therapeutic outcomes. Here we evaluated the ability...

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Hlavní autoři: Karali, Marianthi, Manfredi, Anna, Puppo, Agostina, Marrocco, Elena, Gargiulo, Annagiusi, Allocca, Mariacarmela, Corte, Michele Della, Rossi, Settimio, Giunti, Massimo, Bacci, Maria Laura, Simonelli, Francesca, Surace, Enrico Maria, Banfi, Sandro, Auricchio, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144214/
https://ncbi.nlm.nih.gov/pubmed/21818300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022166
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