CD8(+) T-cell autoreactivity to an HLA-B27–restricted self-epitope correlates with ankylosing spondylitis
HLA-B27 is highly associated with ankylosing spondylitis (AS), but the mechanism is unknown. Among the HLA-B27 alleles, B*2709, which differs by one amino acid from the susceptible B*2705, is not associated with the disease. Here, we analyze the reactivity, in patients with AS and in healthy control...
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| Gepubliceerd in: | J Clin Invest |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2000
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10880047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9295 |
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