Developing Understanding of the Roles of CD1d-restricted T cell Subsets in Cancer: Reversing Tumor-induced Defects

Invariant natural killer T-cells (‘iNKT’) are the best-known CD1d-restricted T-cells, with recently-defined roles in controlling adaptive immunity. CD1d-restricted T-cells can rapidly produce large amounts of Th1 and/or Th2//Treg/Th17-type cytokines, thereby regulating immunity. iNKT can stimulate p...

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Hauptverfasser: Exley, Mark A., Lynch, Lydia, Varghese, Bindu, Nowak, Michael, Alatrakchi, Nadia, Balk, Steven P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143311/
https://ncbi.nlm.nih.gov/pubmed/21646050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2011.04.017
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