Adipose Tissue Invariant NKT Cells Protect Against Diet-Induced Obesity and Metabolic Disorder Through Regulatory Cytokine Production

Invariant Natural Killer T (iNKT) cells are evolutionarily conserved innate T cells that influence inflammatory responses. We have shown that iNKT cells, previously thought to be rare in huamns, were highly enriched in human and murine adipose tissue, and that as adipose tissue expands in obesity, i...

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Gepubliceerd in:Immunity
Hoofdauteurs: Lynch, Lydia, Nowak, Michael, Varghese, Bindu, Clark, Justice, Hogan, Andrew E., Toxavidis, Vasillis, Balk, Steven P., O’Shea, Donal, O’Farrelly, Cliona, Exley, Mark A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991771/
https://ncbi.nlm.nih.gov/pubmed/22981538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.016
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