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Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen

We used intravital microscopy to observe the formation of platelet plugs in ferric chloride–injured arterioles of live mice. With this model, we evaluated thrombus growth in mice lacking von Willebrand factor (vWF) and fibrinogen (Fg), the two key ligands known to mediate platelet adhesion and aggre...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ni, Heyu, Denis, Cécile V., Subbarao, Sangeetha, Degen, Jay L., Sato, Thomas N., Hynes, Richard O., Wagner, Denisa D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC314330/
https://ncbi.nlm.nih.gov/pubmed/10930441
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