Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen

We used intravital microscopy to observe the formation of platelet plugs in ferric chloride–injured arterioles of live mice. With this model, we evaluated thrombus growth in mice lacking von Willebrand factor (vWF) and fibrinogen (Fg), the two key ligands known to mediate platelet adhesion and aggre...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ni, Heyu, Denis, Cécile V., Subbarao, Sangeetha, Degen, Jay L., Sato, Thomas N., Hynes, Richard O., Wagner, Denisa D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10930441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9896
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