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Mutation in the FMN Domain Modulates MCD Spectra of the iNOS Ferric Cyano Complex in a Substrate-Specific Manner
We have obtained low temperature MCD spectra for ferric cyano complexes of the wild type and E546N mutant of a human iNOS oxygenase/FMN construct. The mutation at the FMN domain has previously been shown to modulate the MCD spectra of the L-arginine-bound ferric iNOS heme [Sempombe et al., J. Am. Ch...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143224/ https://ncbi.nlm.nih.gov/pubmed/21718007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic200952c |
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