Eeyarestatin 1 Interferes with Both Retrograde and Anterograde Intracellular Trafficking Pathways

BACKGROUND: The small molecule Eeyarestatin I (ESI) inhibits the endoplasmic reticulum (ER)-cytosol dislocation and subsequent degradation of ERAD (ER associated protein degradation) substrates. Toxins such as ricin and Shiga/Shiga-like toxins (SLTx) are endocytosed and trafficked to the ER. Their c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Aletrari, Mina-Olga, McKibbin, Craig, Williams, Helen, Pawar, Vidya, Pietroni, Paola, Lord, J. Michael, Flitsch, Sabine L., Whitehead, Roger, Swanton, Eileithyia, High, Stephen, Spooner, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143184/
https://ncbi.nlm.nih.gov/pubmed/21799938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022713
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados