Eeyarestatin 24 impairs SecYEG‐dependent protein trafficking and inhibits growth of clinically relevant pathogens

Eeyarestatin 1 (ES1) is an inhibitor of endoplasmic reticulum (ER) associated protein degradation, Sec61‐dependent Ca(2+) homeostasis and protein translocation into the ER. Recently, evidence was presented showing that a smaller analog of ES1, ES24, targets the Sec61‐translocon, and captures it in a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Microbiol
Autori principali: Steenhuis, Maurice, Koningstein, Gregory M., Oswald, Julia, Pick, Tillman, O’Keefe, Sarah, Koch, Hans‐Georg, Cavalié, Adolfo, Whitehead, Roger C., Swanton, Eileithyia, High, Stephen, Luirink, Joen
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273874/
https://ncbi.nlm.nih.gov/pubmed/32798330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14589
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi