Performance of Ultra-Deep Pyrosequencing in Analysis of HIV-1 pol Gene Variation

INTRODUCTION: Ultra-deep pyrosequencing (UDPS) has been used to detect minority variants within HIV-1 populations. Some aspects of the quality and reproducibility of UDPS have been previously evaluated, but comprehensive studies are still needed. PRINCIPAL FINDING: In this study the UDPS technology...

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Bibliographic Details
Main Authors: Mild, Mattias, Hedskog, Charlotte, Jernberg, Johanna, Albert, Jan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143174/
https://ncbi.nlm.nih.gov/pubmed/21799940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022741
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