HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc

BACKGROUND: Maraviroc is an HIV entry inhibitor that alters the conformation of CCR5 and is poorly efficient in patients infected by viruses that use CXCR4 as an entry coreceptor. The goal of this study was to assess the capacity of ultra-deep pyrosequencing (UDPS) and different data analysis approa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rodriguez, Christophe, Soulié, Cathia, Marcelin, Anne-Geneviève, Calvez, Vincent, Descamps, Diane, Charpentier, Charlotte, Flandre, Philippe, Recordon-Pinson, Patricia, Bellecave, Pantxika, Pawlotsky, Jean-Michel, Masquelier, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466260/
https://ncbi.nlm.nih.gov/pubmed/26068869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127816
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