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Activation of PPARδ Enhances Regenerative Capacity of Human Endothelial Progenitor Cells by Stimulating Biosynthesis of BH4

The mechanisms underlying the regenerative capacity of endothelial progenitor cells (EPCs) are not fully understood. We hypothesized that biosynthesis of tetrahydrobiopterin (BH4) is an important mechanism responsible for the stimulatory effects of peroxisome proliferator-activated receptor delta (P...

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Detalhes bibliográficos
Principais autores: He, Tongrong, Smith, Leslie A., Lu, Tong, Joyner, Michael J., Katusic, Zvonimir S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143017/
https://ncbi.nlm.nih.gov/pubmed/21709207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.172189
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