PD-1 blockade by CT-011, anti PD-1 antibody, enhances ex-vivo T cell responses to autologous dendritic/myeloma fusion vaccine

We have developed a cancer vaccine in which autologous tumor is fused with dendritic cells (DCs) resulting in the presentation of tumor antigens in the context of DC mediated costimulation. In clinical trials, immunologic responses have been observed, however responses may be muted by inhibitory pat...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Rosenblatt, Jacalyn, Glotzbecker, Brett, Mills, Heidi, Vasir, Baldev, Tzachanis, Dimitrios, Levine, James D., Joyce, Robin M., Wellenstein, Kerry, Keefe, Whitney, Schickler, Michael, Rotem-Yehudar, Rinat, Kufe, Donald, Avigan, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142955/
https://ncbi.nlm.nih.gov/pubmed/21577144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31821ca6ce
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky