Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation

BACKGROUND: We recently demonstrated that quercetin, a flavonoid naturally present in food and beverages belonging to the large class of phytochemicals, was able to sensitise leukaemic cells isolated from patients with chronic lymphocytic leukaemia (CLL) when associated with recombinant tumour necro...

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Библиографические подробности
Главные авторы: Spagnuolo, C, Cerella, C, Russo, M, Chateauvieux, S, Diederich, M, Russo, G L
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
Предметы:
Translational Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142809/
https://ncbi.nlm.nih.gov/pubmed/21750559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.229
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