Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation

BACKGROUND: We recently demonstrated that quercetin, a flavonoid naturally present in food and beverages belonging to the large class of phytochemicals, was able to sensitise leukaemic cells isolated from patients with chronic lymphocytic leukaemia (CLL) when associated with recombinant tumour necro...

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Bibliografske podrobnosti
Main Authors: Spagnuolo, C, Cerella, C, Russo, M, Chateauvieux, S, Diederich, M, Russo, G L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Translational Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142809/
https://ncbi.nlm.nih.gov/pubmed/21750559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.229
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