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Thiocolchicoside Exhibits Anticancer Effects through Downregulation of NF-κB Pathway and Its Regulated Gene Products Linked to Inflammation and Cancer

The discovery of new uses for older, clinically approved drugs is one way to expedite drug development for cancer. Thiocolchicoside, a semisynthetic colchicoside from the plant Gloriosa superba, is a muscle relaxant and used to treat rheumatologic and orthopedic disorders because of its analgesic an...

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Autors principals: Reuter, Simone, Prasad, Sahdeo, Phromnoi, Kanokkarn, Ravindran, Jayaraj, Sung, Bokyung, Yadav, Vivek R., Kannappan, Ramaswamy, Chaturvedi, Madan M., Aggarwal, Bharat B.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142676/
https://ncbi.nlm.nih.gov/pubmed/20978115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0037
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