α-Fetoprotein impairs activation of natural killer cells by inhibiting the function of dendritic cells

α-Fetoprotein (AFP) is a tumour-associated antigen in hepatocellular carcinoma (HCC). The biological properties of AFP have been identified in its regulatory effects on immune responses of T cells and B cells. However, AFP effects on natural killer (NK) cells are still unclear. In this study, we exa...

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Bibliographic Details
Main Authors: Yamamoto, M, Tatsumi, T, Miyagi, T, Tsunematsu, H, Aketa, H, Hosui, A, Kanto, T, Hiramatsu, N, Hayashi, N, Takehara, T
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Translational Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142646/
https://ncbi.nlm.nih.gov/pubmed/21592114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04421.x
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