The Landscape of C. elegans 3′UTRs

Three-prime untranslated regions (3′UTRs) of metazoan messenger RNAs (mRNAs) contain numerous regulatory elements, yet remain largely uncharacterized. Using polyA capture, 3′ rapid amplification of complementary DNA (cDNA) ends, full-length cDNAs, and RNA-seq, we defined ∼26,000 distinct 3′UTRs in C...

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Autori principali: Mangone, Marco, Manoharan, Arun Prasad, Thierry-Mieg, Danielle, Thierry-Mieg, Jean, Han, Ting, Mackowiak, Sebastian D., Mis, Emily, Zegar, Charles, Gutwein, Michelle R., Khivansara, Vishal, Attie, Oliver, Chen, Kevin, Salehi-Ashtiani, Kourosh, Vidal, Marc, Harkins, Timothy T., Bouffard, Pascal, Suzuki, Yutaka, Sugano, Sumio, Kohara, Yuji, Rajewsky, Nikolaus, Piano, Fabio, Gunsalus, Kristin C., Kim, John K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142571/
https://ncbi.nlm.nih.gov/pubmed/20522740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191244
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