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Pharmacokinetics and behavioral effects of liposomal hydromorphone suitable for perioperative use in rhesus macaques
INTRODUCTION: This study aims to evaluate the pharmacokinetic, behavioral, and motor effects of a liposomal preparation of hydromorphone hydrochloride (LE-hydro) in rhesus monkeys. We administered either 2 mg/kg of LE-hydro (n=8) subcutaneous (s.c.) or 0.1 mg/kg of standard pharmaceutical hydromorph...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142292/ https://ncbi.nlm.nih.gov/pubmed/21404039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2239-y |
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