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Cell-free production of transducible transcription factors for nuclear reprogramming

Ectopic expression of a defined set of transcription factors chosen from Oct3/4, Sox2, c-Myc, Klf4, Nanog, and Lin28 can directly reprogram somatic cells to pluripotency. These reprogrammed cells are referred to as induced pluripotent stem cells (iPSCs). To date, iPSCs have been successfully generat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, William C., Patel, Kedar G., Lee, Jieun, Ghebremariam, Yohannes T., Wong, H. Edward, Cooke, John P., Swartz, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142170/
https://ncbi.nlm.nih.gov/pubmed/19718703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.22517
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