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Cell-free production of transducible transcription factors for nuclear reprogramming
Ectopic expression of a defined set of transcription factors chosen from Oct3/4, Sox2, c-Myc, Klf4, Nanog, and Lin28 can directly reprogram somatic cells to pluripotency. These reprogrammed cells are referred to as induced pluripotent stem cells (iPSCs). To date, iPSCs have been successfully generat...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142170/ https://ncbi.nlm.nih.gov/pubmed/19718703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.22517 |
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