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Orphan nuclear transcription factor TR3/Nur77 regulates microvessel permeability by targeting endothelial nitric oxide synthase and destabilizing endothelial junctions

Low-level basal vascular permeability (BVP) provides nutrients to normal tissues, and increased vascular permeability is characteristic of inflammation and cancer. We recently reported that VEGF-A, a potent vascular permeabilizing and angiogenic factor, exerts much of its angiogenic activity by up-r...

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Bibliografische gegevens
Hoofdauteurs: Zhao, Dezheng, Qin, Liuliang, Bourbon, Pierre-Marie, James, Lauralee, Dvorak, Harold F., Zeng, Huiyan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142008/
https://ncbi.nlm.nih.gov/pubmed/21730126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018438108
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