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Orphan nuclear receptor TR3/Nur77 regulates VEGF-A–induced angiogenesis through its transcriptional activity

Vascular endothelial growth factor (VEGF)-A has essential roles in vasculogenesis and angiogenesis, but the downstream steps and mechanisms by which human VEGF-A acts are incompletely understood. We report here that human VEGF-A exerts much of its angiogenic activity by up-regulating the expression...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zeng, Huiyan, Qin, Liuliang, Zhao, Dezheng, Tan, Xiaolian, Manseau, Eleanor J., Van Hoang, Mien, Senger, Donald R., Brown, Lawrence F., Nagy, Janice A., Dvorak, Harold F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118245/
https://ncbi.nlm.nih.gov/pubmed/16520388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051523
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