Orphan nuclear transcription factor TR3/Nur77 regulates microvessel permeability by targeting endothelial nitric oxide synthase and destabilizing endothelial junctions

Low-level basal vascular permeability (BVP) provides nutrients to normal tissues, and increased vascular permeability is characteristic of inflammation and cancer. We recently reported that VEGF-A, a potent vascular permeabilizing and angiogenic factor, exerts much of its angiogenic activity by up-r...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhao, Dezheng, Qin, Liuliang, Bourbon, Pierre-Marie, James, Lauralee, Dvorak, Harold F., Zeng, Huiyan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142008/
https://ncbi.nlm.nih.gov/pubmed/21730126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018438108
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items