Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use...

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Détails bibliographiques
Auteurs principaux: Walsh, Kevin B., Teijaro, John R., Wilker, Peter R., Jatzek, Anna, Fremgen, Daniel M., Das, Subash C., Watanabe, Tokiko, Hatta, Masato, Shinya, Kyoko, Suresh, Marulasiddappa, Kawaoka, Yoshihiro, Rosen, Hugh, Oldstone, Michael B. A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142000/
https://ncbi.nlm.nih.gov/pubmed/21715659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107024108
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