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Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region

BK channels are regulated by two distinct physiological signals, transmembrane potential and intracellular Ca(2+), each acting through independent modular sensor domains. However, despite a presumably central role in the coupling of sensor activation to channel gating, the pore-lining S6 transmembra...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhou, Yu, Xia, Xiao-Ming, Lingle, Christopher J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141973/
https://ncbi.nlm.nih.gov/pubmed/21730134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104150108
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