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An (1)O(2) Route to γ-Hydroxyalkenal Phospholipids by Vitamin E Induced Fragmentation of Hydroperoxydiene-derived Endoperoxides

Biologically active phospholipids that incorporate an oxidatively truncated acyl chain terminated by a γ-hydroxyalkenal are generated in vivo. The γ-hydroxyalkenal moiety protrudes from lipid bilayers like whiskers that serve as ligands for the scavenger receptor CD36, fostering endocytosis, e.g., o...

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Hlavní autoři: Gu, Xiaodong, Zhang, Wujuan, Choi, Jaewoo, Li, Wei, Chen, Xi, Laird, James M., Salomon, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141739/
https://ncbi.nlm.nih.gov/pubmed/21568309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200093m
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