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An (1)O(2) Route to γ-Hydroxyalkenal Phospholipids by Vitamin E Induced Fragmentation of Hydroperoxydiene-derived Endoperoxides
Biologically active phospholipids that incorporate an oxidatively truncated acyl chain terminated by a γ-hydroxyalkenal are generated in vivo. The γ-hydroxyalkenal moiety protrudes from lipid bilayers like whiskers that serve as ligands for the scavenger receptor CD36, fostering endocytosis, e.g., o...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141739/ https://ncbi.nlm.nih.gov/pubmed/21568309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200093m |
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