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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

Virus infection, double-stranded RNA, and lipopolysaccharide each induce the expression of genes encoding IFN-α and -β and chemokines, such as RANTES (regulated on activation, normal T cell expressed and secreted) and IP-10 (IFN-γ inducible protein 10). This induction requires the coordinate activat...

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Detalhes bibliográficos
Main Authors: McWhirter, Sarah M., Fitzgerald, Katherine A., Rosains, Jacqueline, Rowe, Daniel C., Golenbock, Douglas T., Maniatis, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314168/
https://ncbi.nlm.nih.gov/pubmed/14679297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2237236100
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