A Novel IFN Regulatory Factor 3-Dependent Pathway Activated by Trypanosomes Triggers IFN-β in Macrophages and Fibroblasts

Innate immune recognition of intracellular pathogens involves both extracellular and cytosolic surveillance mechanisms. The intracellular protozoan parasite Trypanosoma cruzi triggers a robust type I IFN response in both immune and nonimmune cell types. In this study, we report that signaling throug...

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Main Authors: Chessler, Anne-Danielle C., Ferreira, Ludmila R. P., Chang, Tun-Han, Fitzgerald, Katherine A., Burleigh, Barbara A.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597000/
https://ncbi.nlm.nih.gov/pubmed/19017982
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