IFN regulatory factor–8 expression in macrophages governs an antimetastatic program

High macrophage infiltration in cancer is associated with reduced survival in animal models and in patients. This reflects a shift in the macrophage response from a tumor-suppressive to tumor-supportive program governed by transcriptional events regulated by the inflammatory milieu. Although several...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Twum, Danielle Y.F., Colligan, Sean H., Hoffend, Nicholas C., Katsuta, Eriko, Cortes Gomez, Eduardo, Hensen, Mary Lynn, Seshadri, Mukund, Nemeth, Michael J., Abrams, Scott I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413790/
https://ncbi.nlm.nih.gov/pubmed/30728331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124267
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