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Disrupted Lymph Node and Splenic Stroma in Mice with Induced Inflammatory Melanomas Is Associated with Impaired Recruitment of T and Dendritic Cells
Migration of dendritic cells (DC) from the tumor environment to the T cell cortex in tumor-draining lymph nodes (TDLN) is essential for priming naïve T lymphocytes (TL) to tumor antigen (Ag). We used a mouse model of induced melanoma in which similar oncogenic events generate two phenotypically dist...
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主要な著者: | , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2011
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141075/ https://ncbi.nlm.nih.gov/pubmed/21811640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022639 |
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