Myeloid IκBα Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques

Activation of the transcription factor NF-κB appears to be involved in different stages of atherogenesis. In this paper we investigate the role of NF-κB inhibitor IκBα in atherosclerosis. Myeloid-specific deletion of IκBα results in larger and more advanced lesions in LDL-R-deficient mice without af...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Goossens, Pieter, Vergouwe, Monique N., Gijbels, Marion J. J., Curfs, Danielle M. J., van Woezik, Johannes H. G., Hoeksema, Marten A., Xanthoulea, Sofia, Leenen, Pieter J. M., Rupec, Rudolf A., Hofker, Marten H., de Winther, Menno P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141029/
https://ncbi.nlm.nih.gov/pubmed/21814576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022327
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados